Status:
UNKNOWN
Effect of Polyphenol Extract on Cardiovascular Health Markers: a 4 Way Randomised Crossover Study
Lead Sponsor:
University of Ulster
Collaborating Sponsors:
University of Parma
Activ'inside
Conditions:
Cardiovascular Diseases
Endothelial Dysfunction
Eligibility:
MALE
20-45 years
Phase:
NA
Brief Summary
Endothelial dysfunction is an early predictor of cardiovascular events in at-risk patients. It is characterized by impaired endothelium-dependent dilation and is primarily caused by reduced nitric oxi...
Eligibility Criteria
Inclusion
- At least two of the following risk markers; a BMI 25-30, waist circumference \>94 cm, high normal blood pressure defined as either systolic 85-89 mmHg or diastolic 130-139 mmHg and have a normal ECG.
Exclusion
- An individual who has tested positive (self reported) 2 weeks before the study period.
- A COVID-19 vaccinated individual who while receive the 1st or 2nd dose or booster 2 weeks before V0 or during the study period, due to the potential interaction of vaccine on markers assessed
Key Trial Info
Start Date :
December 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05220059
Start Date
December 1 2021
End Date
June 30 2022
Last Update
March 11 2022
Active Locations (1)
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1
Human Intervention Studies Unit, Ulster University
Coleraine, Co.Londonderry, United Kingdom, BT52 1SA