Status:
TERMINATED
Discovering FFC-MRI Biomarkers of Alzheimer Disease
Lead Sponsor:
University of Aberdeen
Conditions:
Alzheimer Disease
Eligibility:
All Genders
21-120 years
Phase:
NA
Brief Summary
Fast Field-Cycling MRI (FFC MRI) is a new scanning technology being developed at the University of Aberdeen. Previous pilot studies by the team on osteoarthritis, breast cancer, musculoskeletal cancer...
Detailed Description
Alzheimer's disease (AD) patients and appropriate controls will be identified by consultants working with the patient group. Potential participants will be approached by letter by their clinician. Th...
Eligibility Criteria
Inclusion
- Patients with probable Alzheimer's disease, based upon cognitive testing (MMSE) and SPECT imaging.
- Controls will be participants without known cognitive impairment or Alzheimer's disease.
- Subjects capable of giving informed consent.
- Age 21 and above
Exclusion
- MRI-incompatible condition detected in the MR screening sheet such as some metallic implanted devices (see MR screening sheet in the project files).
- Claustrophobia
- Waist circumference larger than 102 cm, due to the limited bore size of the scanner.
- Restrictions to mobility such that patients are unable to be positioned in scanner by trained research radiographer e.g. severe kyphosis
- Cognitive impairment of sufficient severity that the participant does not have capacity to give informed consent
- Pregnancy
- Persons who might not adequately understand verbal explanations or written information given in English, or who have special communication needs
- Dementia of sufficient severity that the participant cannot give informed consent
Key Trial Info
Start Date :
October 17 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2021
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT05220150
Start Date
October 17 2017
End Date
September 1 2021
Last Update
February 2 2022
Active Locations (1)
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1
Biomedical Physics Building, Foresterhill Health Campus
Aberdeen, Scotland, United Kingdom, AB25 2ZN