Status:

UNKNOWN

Optimal Time Intervals for Vaginal Breech Births: A Multi-Site Case-Control Study

Lead Sponsor:

King's College London

Collaborating Sponsors:

Guy's and St Thomas' NHS Foundation Trust

Conditions:

Intensive Care, Neonatal

Perinatal Death

Eligibility:

FEMALE

Brief Summary

This study uses a case-control design to test the hypotheses that avoidable delay in late second stage and premature cord clamping are associated with admission to the neonatal unit and/or early perin...

Detailed Description

This study replicates a previous successful pilot study (Spillane et al 2021). The sample size calculation for the original study was based on the hypothesis that among those breech births where a neo...

Eligibility Criteria

Inclusion

  • CASES
  • INCLUSION CRITERIA:
  • Singleton pregnancy \> 37+0 weeks with a breech-presenting fetus born vaginally;
  • Alive on admission to intrapartum care
  • Admission to the neonatal unit or early neonatal death (within 6 days of birth);
  • Healthcare professional in attendance.
  • EXCLUSION CRITERIA
  • Births which took place prior to the arrival of a trained health care professional;
  • Major congenital anomaly, identified prior to or after birth, likely to have compromised neonatal condition.
  • CONTROLS
  • INCLUSION CRITERIA:
  • Singleton pregnancy \> 37+0 weeks with a longitudinal breech-presenting fetus born vaginally;
  • No admission to the neonatal unit or early neonatal death (within 6 days of birth);
  • Healthcare professional in attendance;
  • Occurring immediately prior to the matched case; and
  • Matched for parity with that case (nullip/multip).

Exclusion

    Key Trial Info

    Start Date :

    February 1 2022

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    September 30 2023

    Estimated Enrollment :

    225 Patients enrolled

    Trial Details

    Trial ID

    NCT05223140

    Start Date

    February 1 2022

    End Date

    September 30 2023

    Last Update

    February 3 2022

    Active Locations (5)

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    Page 1 of 2 (5 locations)

    1

    Chelsea and Westminster Hospital

    London, United Kingdom, SW10 9NH

    2

    West Middlesex Hospital

    London, United Kingdom, TW7 6AF

    3

    Frimley Health NHS Foundation Trust

    London, United Kingdom

    4

    Guy's and St Thomas' NHS Foundation Trust

    London, United Kingdom