Status:

RECRUITING

Interpretation Bias as a Mechanism of Treatment Response in OCD

Lead Sponsor:

Mclean Hospital

Conditions:

Obsessive-Compulsive Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will conduct a randomized controlled trial of Cognitive Bias Modification for Interpretation (CBM-I) as an augmentation to treatment as usual for obsessive compulsive disorder (OCD). CBM-I ...

Eligibility Criteria

Inclusion

  • 1\) OCD Institute patients
  • 2\) adults (\> 18 years old)
  • 3\) able to complete a computer task for 20 minutes
  • 4\) consent to main OCD Institute study protocol
  • 5\) primary diagnosis of OCD (as measured by a score of \>16 on the Y-BOCS and a clinical diagnosis of OCD by their treatment team
  • 6\) score of \>131 on the Obsessive Beliefs Questionnaire-44 at admission \[which is 1 SD above the mean score of the non-clinical sample reported in the original validation paper by the Obsessive Compulsive Cognitions Working Group (2005)\]

Exclusion

  • 1\) Currently experiencing acute symptoms of psychosis
  • 2\) Psychotic disorder diagnosis

Key Trial Info

Start Date :

March 30 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2026

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT05224414

Start Date

March 30 2022

End Date

August 31 2026

Last Update

May 8 2025

Active Locations (1)

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1

McLean Hospital

Belmont, Massachusetts, United States, 02478

Interpretation Bias as a Mechanism of Treatment Response in OCD | DecenTrialz