Status:
COMPLETED
Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Ketosis
Keto Acidosis
Eligibility:
All Genders
18+ years
Brief Summary
Rationale: During perioperative period, prolonged starvation, surgical stress, acute complications (e.g. infection) and medication changes all promote ketone generation, therefore increasing the risk...
Detailed Description
Study procedures On the first day of admission, all the patients scheduled for cardiac surgery with an on-pump procedure will be asked for a consent for anonymous using of their information. Patients ...
Eligibility Criteria
Inclusion
- In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- Inclusion Criteria
- Aged eighteen years or older
- Scheduled for open heart surgery
- Exclusion criteria
- Diagnosed with type 1 diabetes mellitus or latent auto-immune diabetes in adults
- Recently used sodium glucose transport co-enzyme 2 (SGLT-2i's) within 2 weeks before surgery)
- History of recurrent ketoacidosis (two times or more within three months)
- Emergency surgery
- (Suspected) pregnancy
Exclusion
Key Trial Info
Start Date :
March 15 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 18 2023
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT05225467
Start Date
March 15 2022
End Date
March 18 2023
Last Update
July 20 2023
Active Locations (1)
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1
Amsterdam University Medical Centre
Amsterdam-Zuidoost, North Holland, Netherlands, 1105 AZ