Status:

UNKNOWN

aScope Single Use ERCP Study- ASSURE Study

Lead Sponsor:

Nottingham University Hospitals NHS Trust

Conditions:

ERCP

Cholangitis

Eligibility:

All Genders

18-90 years

Brief Summary

Patients undergo ERCP procedure (Endoscopic procedure with the help of x-rays) for a variety of reasons such as common bile duct (CBD)stones, bile duct obstruction secondary to bile duct narrowing (St...

Detailed Description

ERCP is a therapeutic endoscopic procedure done to establish either bile duct or pancreatic duct drainage or both. The indications for ERCP are bile duct stones, bile duct strictures, sphincter of Odd...

Eligibility Criteria

Inclusion

  • Patients who are at high risk of post ERCP infection such as
  • Jaundice (Bilirubin \>21)
  • Primary sclerosing cholangitis
  • Post liver transplant anastomotic stricture
  • Inpatients
  • Combined procedures (Ex: ERCP+ spy glass cholangioscopy)
  • Previous inadequate biliary drainage.
  • Biliary stricture
  • Participant is willing and able to give informed consent for participation in the study.
  • Male or Female, aged 18 years or above.
  • Grade 1-3 ERCP on complexity grading (ASGE grading)
  • Able (in the Investigators opinion) and willing to comply with all study requirements.
  • Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study.

Exclusion

  • Patients with CBD stones and no jaundice
  • Sphincter of Oddi manometry.
  • Female participants who is pregnant, lactating or planning pregnancy during the course of the study.
  • Patients who are unable to consent for the study.
  • ERCP for Pancreatic pathology.
  • Grade 4 complex ERCP (ASGE grading)
  • Participant who is terminally ill /ECOG 4
  • Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant's ability to participate in the study.

Key Trial Info

Start Date :

April 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 16 2024

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT05225909

Start Date

April 1 2022

End Date

February 16 2024

Last Update

February 7 2022

Active Locations (1)

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1

Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom, Ng7 2UH