Status:

COMPLETED

A Randomized Phase 1 Study of Liralutide Injection in Healthy Chinese Subjects

Lead Sponsor:

The Affiliated Hospital of Qingdao University

Conditions:

Therapeutic Equivalency

Eligibility:

MALE

18+ years

Phase:

PHASE1

Brief Summary

The study was designed as a single-site, randomized, open-label, crossover under fasted conditions. A single oral dose of 0.6 mg Liraglutide injection and Victoza® was given to the 32 healthy Chinese ...

Detailed Description

The study was designed as a single-site, randomized, open-label, crossover under fasted conditions. A single oral dose of 0.6 mg Liraglutide injection and Victoza® was given to the 32 healthy Chinese ...

Eligibility Criteria

Inclusion

  • Healthy male vulunteers aged 18 and above.
  • The body mass index is in the range of 19.0-26.0 kg/m2 (including the critical value).
  • Before the study, all subjects have been informed of the study's purpose, protocal, benefits, and risks, and signed the informed consent voluntarily.

Exclusion

  • Medical examinations revealed clinically significant abnormalities or any evidence or history of clinically significant disease.
  • Volunteers who had used systemic glucocorticoid drugs within 3 months before enrollment.
  • Participation in another clinical trial within 3 months.
  • Smoking more than 5 cigarettes per day during the 3 months prior to screening.
  • Blood donation, massive blood loss (#400mL) or enrolled in other clinical trials 3 months prior to screening.
  • Any use of other prescription drugs (including contraceptive)#over-thecounter drugs, Chinese herbal medicine, health care products and 30 days prior to medication for this study.

Key Trial Info

Start Date :

July 16 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 19 2021

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT05225974

Start Date

July 16 2021

End Date

August 19 2021

Last Update

February 7 2022

Active Locations (1)

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1

Phase I Clinical Research Center

Qingdao, Shandong, China, 266003