Status:

COMPLETED

Repeated EUS-guided Fine Needle Biopsy of Pancreatic Masses After Non-diagnostic or Inconclusive Results

Lead Sponsor:

University of Bologna

Conditions:

Pancreatic Adenocarcinoma

Pancreas Cancer

Eligibility:

All Genders

18-90 years

Brief Summary

The primary aim of REuBio study is to evaluate the diagnostic accuracy of repeated endoscopic ultrasound-guided fine needle biopsy after a previous non-diagnostic or inconclusive EUS-guided sampling o...

Detailed Description

Endoscopic ultrasound-guided fine needles biopsy (EUS-FNB) represents the gold standard method for the diagnosis of solid pancreatic lesions (SPLs), even if a non-negligible risk of false-negative or ...

Eligibility Criteria

Inclusion

  • Age \>18 years old
  • Solid pancreatic mass
  • Previous non diagnostic or inconclusive EUS-tissue aquisition

Exclusion

  • age \< 18 years old
  • pancreatic mass with a predominantly cystic component
  • previous pancreatic tissue acquisition was not performed under EUS-guidance (e.g. percutaneous sampling under abdominal ultrasound-guidance)
  • repetition of pancreatic tissue sampling, after an inconclusive or non-diagnostic result, obtained by other methods than EUS-FNB, such as EUS-FNA or surgery or percutaneous sampling.
  • patients with anatomic alterations or hematologic instability (including presence of severe blood clotting disorders) were excluded.
  • rEUS-FNB of an extra-pancreatic mass

Key Trial Info

Start Date :

July 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 23 2022

Estimated Enrollment :

462 Patients enrolled

Trial Details

Trial ID

NCT05226572

Start Date

July 1 2017

End Date

May 23 2022

Last Update

November 8 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Gastrointestinal Unit, University of Bologna/Hospital of Imola

Bologna, Italy, 40026