Status:

UNKNOWN

Influencing Factors of Helicobacter Pylori Infection and Eradication Failure

Lead Sponsor:

Second Affiliated Hospital of Xi'an Jiaotong University

Conditions:

Helicobacter Pylori Infection

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases, the discovery and eradication of H. pylori infection has great significance to the prevention...

Detailed Description

Taking 300 permanent residents in Xi'an area who will go to the Gastroenterology Clinic of the Second Affiliated Hospital of Xi'an Jiaotong University from February 2022 to March 2023 and undergo 13C-...

Eligibility Criteria

Inclusion

  • Perform 13-UBT,
  • Be able to understand the content of the questionnaire and answer the questions accurately,
  • Permanent residents of Xi'an area,
  • No previous HP eradication treatment,
  • Agree to join the group and sign the informed consent form,
  • Aged between 18-70.

Exclusion

  • Complicated with serious cardiovascular, respiratory, blood, liver, kidney, nerve or endocrine system diseases,
  • Mental disease,
  • Gastric or esophageal surgery history,
  • Severe atypical hyperplasia of gastric epithelium, gastric malignant tumor or other malignant diseases
  • Pregnant or lactating women,
  • Patients with history of penicillin allergy,
  • Allergy to rabeprazole, bismuth dose, clindamycin,
  • Have taken proton pump inhibitors,H2 receptor antagonists, within 2 weeks before participating in the inspection,
  • Have taken herbs that have bacteriostatic effect or antibiotic or bismuth agents within 4 weeks before participating in the inspection.

Key Trial Info

Start Date :

February 6 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2023

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT05226819

Start Date

February 6 2022

End Date

March 1 2023

Last Update

February 8 2022

Active Locations (1)

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1

The second affiliated hospital of Xi'an Jiaotong university

Xi'an, Shaanxi, China, 710004