Status:

UNKNOWN

Study for Detection of Donor-derived Cell-free DNA After Renal Transplantation Using Devysers NGS-based Chimerism Assay.

Lead Sponsor:

Sheba Medical Center

Collaborating Sponsors:

Dan Hauzenberger M.D., Ph.D. Assoc. Professor, Karolinska University Hospital Sweden

Conditions:

Cell-Free Nucleic Acids

Eligibility:

All Genders

20-70 years

Brief Summary

The aim of this study is to evaluate highly sensitive quantitative tests for early molecular detection of graft rejection and associated immune response from liquid biopsies in the blood from patients...

Detailed Description

Each year 40-60 patients undergo renal transplant with a living donor (LD) at Karolinska University Hospital. Prior to transplantation, these patients and their donors are investigated for their immun...

Eligibility Criteria

Inclusion

  • Patients older than 20 undergoing kidney transplantation -

Exclusion

  • Patients included in other studies Patients a combined transplant with other donor Patients not eligible to sign an inform consent Patients with primary non-function or those that lost their graft during the first 3 months
  • \-

Key Trial Info

Start Date :

April 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 31 2024

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05226936

Start Date

April 1 2022

End Date

March 31 2024

Last Update

February 7 2022

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Study for Detection of Donor-derived Cell-free DNA After Renal Transplantation Using Devysers NGS-based Chimerism Assay. | DecenTrialz