Status:
COMPLETED
8 Weeks of L-CIT Supplementation and LIRET on Vascular Function in Hypertensive Postmenopausal Women
Lead Sponsor:
Texas Tech University
Conditions:
Hypertension
Menopause
Eligibility:
FEMALE
50-75 years
Phase:
NA
Brief Summary
The overall objective of this project is to bring forth evidence that L-Citrulline (L-CIT) supplementation and low intensity resistance exercise training (LIRET) alone and combined will improve vascul...
Detailed Description
Individuals who are on medications will refrain from use the morning of all laboratory visits. Participants will be asked to bring medications with them, and will be allowed to ingest it after the vas...
Eligibility Criteria
Inclusion
- Women aged 50-75 years
- Resting systolic BP 120-159 mmHg
- Sedentary (\< 60 min of exercise/week)
- Body mass index of 18.5-39.9 kg/m2)
- Fasting glucose \< 126 mg/dL
- HbA1c \< 6.4%.
Exclusion
- Body mass index ≥ 40 or \< 18.5 kg/m2
- Diagnosed with type 1 or 2 diabetes mellitus
- Cardiovascular diseases
- Systolic blood pressure \> 170 mmHg or on more than two anti-hypertensive medication
- Other chronic diseases such as cancer, asthma, glaucoma, thyroid, kidney, liver and pancreatic disease
- Individuals incorporated in a weight loss program and aerobic or resistance training program
- Heavy smokers (\> 20 cigarettes per day)
- Heavy drinkers (\> 12 alcoholic drinks per week)
Key Trial Info
Start Date :
May 24 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 10 2022
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT05227781
Start Date
May 24 2018
End Date
January 10 2022
Last Update
February 7 2022
Active Locations (1)
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1
Texas Tech University
Lubbock, Texas, United States, 79409