Status:
RECRUITING
Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer
Lead Sponsor:
Zhen-Hai Lu
Conditions:
Advanced Rectal Cancer
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
In the treatment of locally advanced rectal cancer, the short-term and long-term efficacy of the traditional sandwich regimen has not reached satisfactory efficacy. For this reason, the concept of red...
Eligibility Criteria
Inclusion
- Pathological confirmed rectal adenocarcinoma.
- Clinical stage T3-4 or T any N1.With or without MRF positivity, with or without EMVI positivity, R0 resection is estimated.
- No metastasis
- No signs of intestinal obstruction; or intestinal obstruction has been relieved after proximal colostomy surgery.
- Age ranged from 18 to 75
- No previous radiotherapy，surgery and chemotherapy.
Exclusion
- Multiple primary tumor
- Cachexy
Key Trial Info
Start Date :
March 2 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2028
Estimated Enrollment :
121 Patients enrolled
Trial Details
Trial ID
NCT05228431
Start Date
March 2 2022
End Date
May 1 2028
Last Update
April 22 2024
Active Locations (1)
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1
Zhenhai Lu
Guangzhou, Guangdong, China