Status:

COMPLETED

COVID-19 Surveillance in Rural Mozambique for Prompt and Effective Response

Lead Sponsor:

Centro de Investigacao em Saude de Manhica

Collaborating Sponsors:

Barcelona Institute for Global Health

Imperial College London

Conditions:

COVID-19

Eligibility:

All Genders

Brief Summary

Extraordinary times require extraordinary measures. The current COVID-19 pandemic is the paradigmatic example of how infectious diseases may menace the world's health and economy, and particularly con...

Detailed Description

Although Mozambique has so far had few confirmed cases of COVID19, it is unknown if low testing rates and other factors such as the warm climatic conditions may explain the apparently low spread of th...

Eligibility Criteria

Inclusion

  • Inclusion Criteria The study has five components and therefore the inclusion criteria may vary from one component to another.
  • COVID-19 morbidity surveillance
  • Individuals of any age admitted to MDH or pregnant attending the Maragra health center meet the COVID-19 case definition as defined above after the project start date.
  • Resident of Manhiça DSS area
  • Written informed consent from a parent or guardian if a child, and from participant if an adult prior recruitment.
  • COVID-19 mortality surveillance • All deaths in children under the age of 5 (including stillbirths), occurring at the health facility or at the community; • In hospital adult deaths occurring at the MDH;
  • • Resident of Manhiça DSS area;
  • • Written informed consent from the relative of the dead person.
  • COVID-19 population-based serosurveys • Individuals of all age groups residing in Manhiça DSS surveillance area • Signed informed parental permission from a parent or guardian if a child and from participant if an adult.
  • Natural history of SARS-CoV-2 infection
  • • Participants who fulfill eligibility criteria for activity a) and with laboratory-confirmed SARS-CoV-2 infection.
  • Clinical presentation and factors associated with SARS-CoV-2 • Participants who fulfill eligibility criteria for activities a) and c).
  • Exclusion Criteria
  • • Participation in an interventional clinical trial at the time of enrollment.

Exclusion

    Key Trial Info

    Start Date :

    December 1 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    August 31 2022

    Estimated Enrollment :

    6494 Patients enrolled

    Trial Details

    Trial ID

    NCT05228639

    Start Date

    December 1 2020

    End Date

    August 31 2022

    Last Update

    August 31 2023

    Active Locations (1)

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    1

    Centro de investigacao em saude de Manhica

    Manhiça, Mozambique