Status:
UNKNOWN
NIRS and Exercise Intensity in Patients With FLIA
Lead Sponsor:
Maxima Medical Center
Conditions:
Near-Infrared Spectroscopy
Iliac Artery Stenosis
Eligibility:
All Genders
18-40 years
Brief Summary
The research objectives of this project are to increase the understanding of pathophysiology and performance limitations related to sport-related flow limitation in the iliac artery (FLIA) using non-i...
Detailed Description
A professional cyclist covers approximately 25,000 km a year and flexes the hip 8,000,000 times in a year, while leg blood flow is in the range of 10-15 litres per minute. This poses a substantial hem...
Eligibility Criteria
Inclusion
- Aged ≥ 18 years and ≤ 40 years
- Trained cyclist or triathlete regularly training at least \~3/week for at least five years and identifying with a particular cycle-sport
Exclusion
- Earlier vascular iliac surgery
- Microvascular abnormalities (e.g. diabetes),
- Vascular abnormalities outside of the iliac region,
- Heart failure (New York Heart Association class \>I),
- Orthopedic/neurological entities potentially limiting exercise capacity,
- Obesity.
- Adipose tissue thickness \> 7.5 mm
- These excluding conditions are considered as medical safety precautions to maximal exercise or as risk of unexpected pathophysiological effects confounding our primary outcome measures.
- It is known that a high level of adipose tissue thickness (ATT) influences the accuracy of NIRS measurement of underlying muscular tissue. A \> 7.5 mm ATT cut-off point at the site of NIRS measurement determined with a skinfold caliper (Harpenden, Baty International West Sussex, UK) was chosen. The ATT is calculated as half the skinfold thickness.
Key Trial Info
Start Date :
May 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05229250
Start Date
May 1 2022
End Date
November 1 2023
Last Update
April 14 2022
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