Status:
COMPLETED
Exercise in Older Adults at Risk for Type 2 Diabetes
Lead Sponsor:
Western University, Canada
Conditions:
Cognitive Change
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
Older adults with type 2 diabetes experience neurocognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (i.e., those who a...
Detailed Description
The effects of exercise on cognition and brain structure in older adults at risk for type 2 diabetes: A 3T MRI study Objectives/research questions: In this study the research questions included: 1....
Eligibility Criteria
Inclusion
- Community-dwelling
- Aged 60-80 years
- "At-risk" for diabetes, where they have one of the following: i) blood glucose level of 6.1-7 mmol/L, ii) body mass index \> 25, or iii) score \> 21 on the CANRISK diabetes questionnaire
- Score \> 24/30 on MMSE
- Score \> 6/8 on the IADL scale
- Visual acuity of at least 20/40, with or without corrective lenses
- Speak and understand English fluently
- Complete the PAR-Q
- Obtain physician's clearance to start a supervised exercise program
Exclusion
- Current medical condition for which exercise is contraindicated
- Participated regularly in resistance or aerobic training in the last 6 months
- Diagnosed with neurodegenerative disease (including dementia, Alzheimer's disease, or Parkinson's disease)
- Experienced a vascular incident (e.g., stroke, myocardial infarction)
- Diagnosed with a psychiatric condition
- Untreated depression and scored 5 or less on the Geriatric Depression Scale
- Currently on hormone replacement therapy
- Clinically significant peripheral neuropathy or severe musculoskeletal or joint disease
- Currently taking psychotropic medications
- Cannot blood draw
Key Trial Info
Start Date :
September 23 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 5 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05229705
Start Date
September 23 2022
End Date
June 5 2024
Last Update
October 15 2024
Active Locations (1)
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1
Western University
London, Ontario, Canada, N6A 5B7