Status:

COMPLETED

Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel Obstruction

Lead Sponsor:

Karaganda Medical University

Collaborating Sponsors:

Ministry of Education and Science, Republic of Kazakhstan

Conditions:

Intestinal Obstruction

Colorectal Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Despite modern approaches to the diagnosis and treatment of acute bowel obstruction (ABO), postoperative mortality ranges from 5 to 32%, and complications occur up 23% of cases. One of the formidable ...

Detailed Description

For the early diagnosis of infectious and inflammatory complications, it is necessary to study LBP, sCD-14 and 16sRNA as bacterial translocation markers in patients with malignant and benign acute bow...

Eligibility Criteria

Inclusion

  • patients with malignant acute bowel obstruction,
  • patients with benign acute bowel obstruction,
  • colorectal cancer patients without acute bowel obstruction (planned operations).

Exclusion

  • age less than 18,
  • pregnancy,
  • patients with paralytic acute bowel obstruction,
  • patients with HIV infection, liver cirrhosis,
  • patient with an infectious process due to another pathology.

Key Trial Info

Start Date :

March 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2023

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT05229822

Start Date

March 1 2021

End Date

December 31 2023

Last Update

January 16 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

NJSC Karaganda Medical University

Karaganda, Kazakhstan, 100000