Status:
COMPLETED
Paracetamol Vs Caffeine Vs Codeine in the Management of Post Traumatic Pain in Emergencies
Lead Sponsor:
University of Monastir
Conditions:
Acute Pain Due to Trauma
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to: Compare the effect of paracetamol alone against Paracetamol+Codeine association against the association of paracetamol + Cafeine in the treatment of post-traumatic ac...
Detailed Description
At admission to the emergency department, patients with acute post-traumatic pain will be included, regardless of their initial NRS .These patients will receive the necessary care for their injury (ic...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Age :18 years or older
- Patients presented to the emergency department with acute post-traumatic pain and residual pain at rest and/or on movement with a numerical pain rating scale (NRS) \> 3/10 on discharge.
- They all signed a written consent form.
- Exclusion criteria:
- Self-mutilation
- Severe acute trauma that may require hospitalization
- Open or complicated fracture requiring surgical management
- Regular use of analgesics
- Any known allergy to paracetamol, caffeine or codeine
- Asthma and acute/chronic respiratory insufficiency
- Severe renal insufficiency (creatinine Cl\<30 ml/min)
- Pregnant/lactating women
- Hepatic cirrhosis.
- Refusal, incapacity or difficulties to consent or to communicate
Exclusion
Key Trial Info
Start Date :
November 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 27 2023
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT05229965
Start Date
November 1 2022
End Date
June 27 2023
Last Update
June 28 2023
Active Locations (1)
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1
Nouira Semir
Monastir, Tunisia, 5000