Status:
COMPLETED
Pecan Consumption and Cognitive Function
Lead Sponsor:
University of Georgia
Conditions:
Healthy
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
Human cognitive function is affected by age-related changes, with some areas beginning to decline in mid-adulthood and worsening with age. However, there is evidence that dietary interventions or the ...
Detailed Description
This trial will be a double-blinded, randomized, cross-over design in humans. There will be two study visits for two different test meals administered in random order. The two testing visits (v1 and v...
Eligibility Criteria
Inclusion
- 18 to 30-years-old
- Healthy individuals
- Men and Women
- Normal body mass index (BMI) (18.5-24.9kg/m2). If BMI is 25 or greater, subjects can still qualify if their body fat percentage falls within healthy ranges defined as Men: 5-20%, and Women: 15-30% \[22\]
- Individuals with normal or corrected to normal vision
- Low-risk alcohol use as assessed by the AUDIT questionnaire (need a score of 7 or lower)
- No or minimal depression symptoms as indicated by the Beck's Depression Inventory (need a score of 9 or lower)
- Cognitive competence for education level and age as measured by the Mini-Mental State Examination (need a score of 26 or higher)
Exclusion
- All chronic diseases (including, but not limited to, renal or bowel diseases, cardiovascular disease, and any form of diabetes)
- Known neurological, cognitive, or psychiatric conditions (including, but not limited to, mood disorders, anxiety disorders, and depression)
- Prescription medication use (with the exception of female contraception methods)
- Dietary supplement use (including, but not limited to, multivitamins and fish oil supplements)
- Alcohol intake \>3 drinks/d for males or \>2 drinks/d for females
- Diagnosis of ADHD or a learning difficulty (including, but not limited to, dyslexia)
- History of head injury (defined as loss of consciousness more than 10 minutes)
- History of inflammatory disorders (including, but not limited to, migraines, stroke, hypertension, hypercoagulation, vascular disease, thyroid conditions, blood disorders, coagulation disorders)
- Food allergies/sensitivities to foods provided in this protocol including tree nuts, gluten, and or lactose/dairy
- Regular consumption of nuts and/or nut butters defined as consumption of \>2 servings (60g) of tree nuts or nut butters (e.g., peanut butter, almond butter) per week
- High caffeine consumption, defined as \>400mg/d
- Individuals adhering to special diets (including, but not limited to, the ketogenic diet, intermittent fasting, Atkins diet, vegan diet, vegetarian diet, or carbohydrate-restricted diets)
- Illicit drug use
- Smoking or use of tobacco products
- Color-blindness
- History of current renal or bowel disease
- Females who are currently pregnant or lactating
- Active individuals (defined as performing \>5 hours/week of scheduled exercise)
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 25 2023
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT05230212
Start Date
February 1 2021
End Date
February 25 2023
Last Update
April 14 2023
Active Locations (1)
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1
University of Georgia- Department of Foods and Nutrition
Athens, Georgia, United States, 30605