Status:

NOT_YET_RECRUITING

CME Versus Standard Right Hemicolectomy for Right Sided Cancers

Lead Sponsor:

Odense University Hospital

Conditions:

Colon Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Our aim of this study is to compare the difference in lymph node yield in CME specimens versus those patients having a standard right hemicolectomy for right sided cancer .The secondary aim of this st...

Detailed Description

CRC is the third most common cancer in men and second most common in women with almost 55% of these cases occurring in more developed nations Findings from a recent population-based study showed that ...

Eligibility Criteria

Inclusion

  • Participant is willing and able to give informed consent for participation in the trial.
  • Male or Female, aged 18 years or above.
  • Undergoing CME or standard right hemicolectomy surgery for right-sided cancer after MDT discussion.
  • Cancer must be confirmed by histological, radiological, endoscopic diagnosis
  • In the Investigator's opinion, is able and willing to comply with all trial requirements.

Exclusion

  • Female participant who is pregnant, lactating or planning pregnancy during the course of the trial.
  • Participant with life expectancy of less than 6 months.
  • Distal Transverse colon and splenic flexure tumors
  • Evidence of T4 disease invading adjacent organs
  • Synchronous surgical procedure planned with CME or right hemicolectomy
  • Urgent, unplanned or emergency surgery
  • Neoadjuvant chemotherapy administered to treat this cancer prior to resection
  • Concurrent or previous abdominal or pelvic malignancy within five years prior to registration irrespective of treatment modality
  • Known Crohn's disease with active terminal ileal disease
  • Evidence of systemic disease (cardiovascular, renal, hepatic, etc.) that would preclude surgery, or other severe incapacitating disease, i.e. ASA IV (a patient with severe systemic disease that is a constant threat to life) or ASA V (a moribund patient who is not expected to survive without the operation).
  • Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the trial, or may influence the result of the trial, or the participant's ability to participate in the trial.

Key Trial Info

Start Date :

March 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2028

Estimated Enrollment :

330 Patients enrolled

Trial Details

Trial ID

NCT05230329

Start Date

March 1 2022

End Date

February 1 2028

Last Update

February 8 2022

Active Locations (1)

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Issam al-Najami

Svendborg, Southern Denmark, Denmark, 5700