Status:
UNKNOWN
The Impact of Electroacupuncture Combined With NGF on Clinical Effect and Functional Changes on Ischemic Stroke
Lead Sponsor:
The Third Affiliated hospital of Zhejiang Chinese Medical University
Collaborating Sponsors:
Ningbo No.2 Hospital
second people hospital of lishui
Conditions:
Ischemic Stroke
Eligibility:
All Genders
50-80 years
Phase:
PHASE4
Brief Summary
Ischemic stroke is a common clinical disease, often accompanied by motor dysfunction and cognitive impairment. At present, clinical treatment for patients with ischemic stroke recovery is limited and ...
Eligibility Criteria
Inclusion
- people with first-ever ischemic stroke confirmed by CT or/and MRI;
- 14 days to 6 months after stroke onset;
- 50 years≤aged≤80 years;
- 3≤modified Rankin Score (mRS)≤4, and Mini-Mental State Examinations (MMSE)\<27;
- Patients can accept treatment with EA and have good compliance;
- Patients have clear consciousness, pain perception and resolution ability to complete basic communication;
- willing to participate and be randomized to one of the groups.
Exclusion
- transient ischemic attack, subarachnoid hemorrhage, cerebral hemorrhage and other cerebrovascular diseases;
- severe heart, liver, kidney dysfunction and severe coagulation dysfunction;
- cerebral infarction caused by repeated recurrence of stroke, brain surgery or trauma, and brain tumors;
- severe neurological deficits before stroke, such as visual and auditory impairment, aphasia, agnosia, severe hemiplegia, or affected limb function before stroke, such as cerebral palsy, polio, fracture, and mRs≥1;
- diseases with affecting cognitive function such as congenital dementia, or alcohol, drug or substance abuse;
- lactation, pregnancy or intend to be pregnant within 6 months;
- needlesickness, needle phobia and skin infection at acupuncture site;
- pacemaker, implantable cardioverter defibrillator carriers or conductive metallic foreign bodies in the body;
- allergy to NGF;
- currently enrolled in another clinical trial or participation in other clinical trials within the last 3 months.
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
288 Patients enrolled
Trial Details
Trial ID
NCT05231694
Start Date
April 1 2022
End Date
December 31 2025
Last Update
July 28 2022
Active Locations (1)
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1
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Hangzhou, Zhejiang, China, 310000