Status:
UNKNOWN
Endoscopic Vital Nerve Staining in Gastrointestinal Diseases
Lead Sponsor:
Affiliated Hospital to Academy of Military Medical Sciences
Conditions:
Gastrointestinal Neoplasms
Abnormality of Enteric Nervous System Morphology
Eligibility:
All Genders
18-70 years
Phase:
EARLY_PHASE1
Brief Summary
In this study, methylene blue (MB) was used as vital nerve staining agent. During gastroenteroscopy, mucosal nerve staining was achieved by endoscopic submucosal injection of MB solution. To observe t...
Detailed Description
This study is a prospective experimental study. The baseline data of the patients were recorded objectively: sex, age, vital signs, body weight, some laboratory examination results (blood routine, liv...
Eligibility Criteria
Inclusion
- Diagnosis or suspected diagnosis of one of the following common gastrointestinal diseases: chronic non-atrophic gastritis, chronic atrophic gastritis, gastric polyps, gastric early cancer, advanced gastric cancer; colonic polyps, colonic Melanosis, early colon cancer, advanced colon cancer
- Written informed consent
Exclusion
- Those who are allergic to nerve dye components (such as methylene blue, etc.)
- Complicated with cardiovascular and cerebrovascular diseases, or severely impaired liver, kidney and hematopoietic system.
- Psychopath
- There are hemorrhagic diseases
- Platelet count \< 50 × 10 \^ 9 / L
- Those who are allergic to body mass are
- Unable to tolerate or cooperate with endoscopy
- Patients with serious complications, such as severe infection, gastrointestinal bleeding, obstruction and perforation, etc.
- Pregnant or lactating women
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 15 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05232357
Start Date
March 1 2022
End Date
May 15 2022
Last Update
March 15 2022
Active Locations (1)
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1
The First Medical Center of Chinese PLA General Hospital
Beijing, Beijing Municipality, China, 100853