Status:

COMPLETED

The Effect of Enalapril, Losartan or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Lead Sponsor:

Unidad de Investigacion Medica en Enfermedades Renales

Conditions:

Oxidative Stress

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

The clinical and biochemical improvement observed in kidney transplant (RT) recipients is remarkable. The correct functioning of the allograft depends on various factors such as the donor's age, the a...

Detailed Description

An open, randomized clinical trial is proposed with a control group. It is carried out in the Transplant Division of the High Specialty Medical Unit of the Hospital de Especialidades, Centro Médico Na...

Eligibility Criteria

Inclusion

  • Renal trasplant, from a living related donor (DVR) or living unrelated donor (DVNoR)
  • Who agreed to participate and signed the Letter of Consent under Information.

Exclusion

  • Patients who received an RT from a deceased donor,
  • With donor \>55 years,
  • With renal comorbidities at the time of the study (urolithiasis, infections, diabetes),
  • With blood dyscrasias,
  • Second transplantation,
  • Those with treatment with non-steroidal anti-inflammatory drugs,
  • Treatment with statins, spironolactone, pentoxifylline, patients
  • With neurodegenerative processes
  • Those who withdrew the Letter of Consent under Information

Key Trial Info

Start Date :

January 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 6 2022

Estimated Enrollment :

39 Patients enrolled

Trial Details

Trial ID

NCT05232370

Start Date

January 1 2022

End Date

January 6 2022

Last Update

February 9 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Enrique Rojas Campos

Guadalajara, Jalisco, Mexico, 44320