Status:
ACTIVE_NOT_RECRUITING
Effects of t-DCS and Cognitive Training on Apathy in Elderly With Minor Neurocognitive Impairment
Lead Sponsor:
Centre Hospitalier Universitaire de Nice
Conditions:
Apathy
Neurocognitive Disorders
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique using a low intensity electric current to modify cortical excitability. Apathy is a pervasive neuropsychiat...
Detailed Description
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique using a low intensity electric current to modify cortical excitability. There is growing interest for tDCS ...
Eligibility Criteria
Inclusion
- Age ≥ 65 years
- Subject consulting in one of the investigating centers
- Clinical diagnosis of Minor Neurocognitive Disorder according to DSM 5 criteria (APA, 2013)
- Apathetic syndrome defined according to the Diagnostic Criteria for Apathy (Miller \& al., 2021)
- Subject who can read and write French
- Subjects who are beneficiaries of a social security plan
- Signature of free and informed consent
Exclusion
- Current clinical diagnosis of a depressive episode characterized by DSM 5 criteria (APA, 2013)
- Known diagnosis of schizophrenia, bipolar disorder, substance abuse or dependence
- Significant sensory or motor impairment
- Subject under guardianship, conservatorship, or conservatorship
- Active smoking or smoking cessation of less than one year
- Contraindications to the practice of tDCS: history of intracranial hypertension, neurosurgery, metallic implant at the cephalic level, pacemaker
- Unbalanced epilepsy
- Severe somatic disease not stabilized
- Previous use of tDCS (problem of maintaining the integrity of the blinding procedure)
- Scalp skin disease
- Concurrent participation in another drug research study or any other study that may interfere with study results
Key Trial Info
Start Date :
April 5 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 10 2026
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT05232877
Start Date
April 5 2022
End Date
June 10 2026
Last Update
November 26 2025
Active Locations (1)
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1
Centre Memoire Ressources et Recherche, CHU de Nice
Nice, France, 06000