Status:
COMPLETED
Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment
Lead Sponsor:
University of Beykent
Conditions:
Periodontal Diseases
Periodontal Attachment Loss
Eligibility:
All Genders
Phase:
NA
Brief Summary
The present study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to non-surgical periodontal treatment (NSPT) on the plasminogen-activating system in Stage 3-4, Grade...
Detailed Description
Limited data is available regarding the effects of various periodontal treatment protocols on GCF t-PA and PAI-1 levels, and the extent to which LLLT in conjunction with NSPT affects these levels in p...
Eligibility Criteria
Inclusion
- Stage 3-4, Grade C periodontitis (at least one site with probing depth (PD) and clinical attachment level (CAL) ≥5 mm in their incisors and/or first molars and at least 6 other teeth with similar PD and CAL measurements, with alveolar bone loss confirmed by radiography; familial aggregation;
- presence of ≥16 teeth;
- no periodontal treatment in the 6 months prior to data collection;
- non-smoker
Exclusion
- systemic problems, including a medical history of cancer, rheumatoid arthritis, diabetes mellitus, or cardiovascular disease;
- compromised immune system;
- pregnancy, menopause, or lactation;
- ongoing drug therapy that might affect the clinical characteristics of periodontitis;
- use of systemic antimicrobials during the 6 weeks prior to data collection
Key Trial Info
Start Date :
January 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 30 2018
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT05233501
Start Date
January 1 2017
End Date
August 30 2018
Last Update
February 10 2022
Active Locations (1)
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1
Beykent University
Istanbul, Turkey (Türkiye)