Status:
TERMINATED
Flow Rate Impact on Arterial Carbon Dioxide During THRIVE
Lead Sponsor:
Uppsala University Hospital
Conditions:
Apneic Oxygenation
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Apneic oxygenation describes the process of continuous oxygenation of the blood without breathing efforts. This anesthesia technique has been described in the literature for more than 100 years and is...
Detailed Description
Eligible participants with signed informed consent presenting for elective surgery will have standard monitoring with ECG, pulse oximetry, blood pressure, train-of-four monitoring and capnography appl...
Eligibility Criteria
Inclusion
- Patients presenting for elective surgery
Exclusion
- Age \<18 or \>65 years
- Body Mass Index (BMI) \>35 kg m-2
- American Society of Anesthesiology classification \> 2
- Physical activity level less than 5 metabolic equivalents
- Obstruction of the upper airways
- Known or high clinical suspicion of difficult airway
- Obstructive sleep apnea syndrome
- Increased risk of aspiration
- Pulmonary or cardiac condition resulting in a reduction of physical activity level equivalent to the New York Heart Association class of 2 or higher.
- Any contraindication to high-flow nasal oxygen therapy or hypercapnia
- Pregnancy or breastfeeding
- Allergy to any of the anesthetic agents used in the study
- Inability to comprehend oral or written information.
Key Trial Info
Start Date :
February 8 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 13 2024
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT05234424
Start Date
February 8 2022
End Date
May 13 2024
Last Update
May 16 2024
Active Locations (1)
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1
Uppsala University Hospital
Uppsala, Uppsala County, Sweden, 75185