Status:

COMPLETED

The Effect of the CytoSorb® Filter to Remove Anticoagulants From the Circulation During Emergency Surgery for Aortic Dissection

Lead Sponsor:

Oslo University Hospital

Collaborating Sponsors:

University of Oslo

Conditions:

Aortic Dissection

Factor X Inhibition

Eligibility:

All Genders

18-100 years

Brief Summary

The direct oral anticoagulants (DOACs) and particularly the FXa inhibitors are a concern in patients presenting with type A aortic dissection as this may contribute to severe bleeding complications. T...

Eligibility Criteria

Inclusion

  • Indication for urgent surgery for proximal aortic disease
  • Treatment with FXa inhibitor for more than 2 weeks
  • Measured concentration of FXa inhibitor in therapeutic range (\>50 ng/mL) at the time of admission.
  • Intraoperative use of Cytosorb® hemadsorber.

Exclusion

  • • Low FXa inhibitor concentration (\<50 ng/mL) at the time of admission

Key Trial Info

Start Date :

April 18 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 5 2024

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT05235178

Start Date

April 18 2021

End Date

November 5 2024

Last Update

May 14 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Oslo University Hospital

Oslo, Oslo County, Norway, 0450

The Effect of the CytoSorb® Filter to Remove Anticoagulants From the Circulation During Emergency Surgery for Aortic Dissection | DecenTrialz