Status:
COMPLETED
Right vEntricular Function Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia.
Lead Sponsor:
University Hospital Plymouth NHS Trust
Collaborating Sponsors:
University of Plymouth
Conditions:
Bronchopulmonary Dysplasia
Right Ventricular Dysfunction
Eligibility:
All Genders
2-2 years
Brief Summary
Short title REPORT-BPD feasibility study Design A mixed methods observational cohort feasibility study Study Setting Neonatal Intensive Care Unit at University Hospitals Plymouth NHS Trust Aim To e...
Detailed Description
RATIONALE The current research findings demonstrated a persistently elevated myocardial performance index of the right ventricle (RV) in the first two weeks of postnatal life (WoPL) in preterm infants...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA
- Born at \< 32 weeks gestational age.
- The echo scans are indicated as per the recommended neonatal practice:
- Preterm infants who require mechanical ventilation or non-invasive respiratory support (CPAP ≥ 4 cm H2O, High Flow ≥ 4 L/min).
- Detection of a cardiac murmur in the first three days after birth.
- Assessment of patent ductus arteriosus (PDA).
- Preterm infants have central line in-situ, so echo is needed to assess line position.
- EXCLUSION CRITERIA
- Preterm infants with major congenital anomalies, such as pulmonary hypoplasia or congenital heart disease (except PFO or PDA).
- Preterm infants with a poor prospect of survival.
- Preterm infants whose parents do not consent.
- Preterm infants who are still in need of blood pressure supporting medications, such as, (inotropes) when the study echo scans are due.
- Preterm infants need inhaled nitric oxide gas when the study echo scans are due.
- PDA - patent ductus arteriosus, PFO - patent foramen ovale
Exclusion
Key Trial Info
Start Date :
June 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 5 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05235399
Start Date
June 1 2022
End Date
May 5 2023
Last Update
August 1 2023
Active Locations (1)
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1
University Hospital Plymouth NHS Trust (UHP)
Plymouth, Devon, United Kingdom, PL6 5FP