Status:
UNKNOWN
Neuropsychological and Neuroimaging Evaluation of the Cognitive Impairment in Aortic Valve Replacement (ARTiCO)
Lead Sponsor:
Germans Trias i Pujol Hospital
Collaborating Sponsors:
Instituto de Salud Carlos III
Conditions:
Aortic Valve Stenosis
Transcatheter Aortic Valve Replacement
Eligibility:
All Genders
70-85 years
Brief Summary
OBJECTIVE: To evaluate changes in cognitive performance in the early postoperative (1 month) and late (1 year) postoperative period in patients undergoing aortic valve replacement (SVAo) with surgery ...
Detailed Description
Design: Prospective, single-center, longitudinal cohort study with consecutive inclusion of patients older than 70 years of intermediate or high surgical risk who present Aortic Stenoses (AoS) that re...
Eligibility Criteria
Inclusion
- presence of severe / symptomatic aortic stenosis with indication for elective Aortic Valve Replacement
- patients with intermediate or high surgical risk evaluated by EuroScore II 3-10%, susceptible to be treated with both techniques
- age\> 70 years
Exclusion
- contraindication to perform an MRI
- severe renal failure
- severe psychiatric illnesses
- Diagnosed dementia or Mini Mental State Examination (MMSE) \<19/35 corrected for age and education
- surgical reintervention
- patients with preoperative comorbidities that condition difficulties for a one-year clinical follow-up
- aortic surgery concomitant to AVS or other than coronary revascularization
Key Trial Info
Start Date :
January 4 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT05235529
Start Date
January 4 2021
End Date
December 1 2023
Last Update
February 11 2022
Active Locations (1)
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1
Meritxell Gomis Cortina
Badalona, Barcelona, Spain, 08917