Status:
COMPLETED
VascuFit: Exercise and Vascular Aging
Lead Sponsor:
Karsten Königstein
Collaborating Sponsors:
University of Basel
QIAGEN Gaithersburg, Inc
Conditions:
Endothelial Function
Aerobic Exercise
Eligibility:
MALE
40-60 years
Phase:
NA
Brief Summary
Exercise is a cornerstone of health care helping to improve and maintain a good organ functionality, including vascular function, in health and disease. About twenty years ago, the introduction of hig...
Detailed Description
A detailed description of the study can be found at: DOI: 10.1186/s12872-022-02905-1
Eligibility Criteria
Inclusion
- Informed consent, documented by signature
- sedentary lifestyle, as not performing exercise on a regular basis and reaching less than the recommended 7.5 MET hours of at least moderate intensity activity per week
- being mentally and physically able to attend and keep up training during the whole intervention period.
Exclusion
- current or chronic condition limiting exhaustive exercise (e.g. heart failure, infection, pulmonary disease)
- any condition with elevated risk of a serious adverse event during exhaustive exercise (e.g. cardiomyopathy, acute myocardial infarction, stroke, uncontrolled hypertensive resting blood pressure ≥160/100mmHg)
- chronic condition with severe affection of the vascular system (e.g. severe atherosclerosis, severe chronic kidney disease, autoimmune vasculitis, insulin dependent diabetes mellitus)
- inability to follow advice during measurements and training sessions (e.g. language barriers, psychological disorders, dementia)
- previous enrollment into the current study or participation in another study in the last four weeks.
Key Trial Info
Start Date :
May 2 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2023
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT05235958
Start Date
May 2 2022
End Date
February 28 2023
Last Update
December 4 2023
Active Locations (1)
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1
Departement of Sport, Exercise and Health
Basel, Switzerland, 4052