Status:
COMPLETED
Appeal of Nicotine Pouches Versus Cigarettes in the Ohio Appalachia Population
Lead Sponsor:
Ohio State University Comprehensive Cancer Center
Conditions:
Cigarette Smoking-Related Carcinoma
Eligibility:
All Genders
21+ years
Phase:
EARLY_PHASE1
Brief Summary
This clinical trial estimates the abuse liability of nicotine pouches with varying nicotine concentrations relative to cigarette smoking in Appalachian, Ohio and Ohio smokers. Nicotine pouches are a n...
Detailed Description
Aim 1: PRIMARY OBJECTIVE: I. To estimate the abuse liability of nicotine pouches (NPs) with varying nicotine concentrations relative to cigarette smoking. SECONDARY OBJECTIVE: I. To clarify the pu...
Eligibility Criteria
Inclusion
- Aim 1
- Age 21 years or older.
- Reside in an Ohio Appalachian county.
- Willing to complete study procedures, including abstaining from all tobacco, nicotine, and marijuana for 12 hours before clinic visits.
- Ability to read and speak English.
- Smoke at least 5 cigarettes per day for the past 30 days.
Exclusion
- Use tobacco products other than cigarettes \>10 days per month.
- Use NP in the past 3 months.
- Unstable or significant psychiatric conditions (past and stable conditions will be allowed).
- Pregnant, planning to become pregnant, or breastfeeding.
- History of cardiac event or distress within the past 3 months.
- Currently attempting to quit all tobacco use.
- Self-reported diagnosis of lung disease including asthma (if uncontrolled or worse than usual), cystic fibrosis, or chronic obstructive pulmonary disease.
- Aim 2 Inclusion Criteria:
- Age 21 years or older.
- Reside in a Ohio.
- Willing to complete study procedures, including abstaining from all tobacco, nicotine, and marijuana for 12 hours before clinic visits.
- Ability to read and speak English.
- Smoke at least 5 cigarettes per day for the past 30 days.
Key Trial Info
Start Date :
March 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 18 2023
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT05236894
Start Date
March 1 2022
End Date
April 18 2023
Last Update
May 21 2024
Active Locations (1)
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1
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210