Status:

ACTIVE_NOT_RECRUITING

Non-surgical vs. Surgical Therapy for Periodontal Furcations

Lead Sponsor:

King's College London

Conditions:

Furcation Defects

Periodontitis

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

Periodontitis is an inflammatory disease of the tooth-supporting apparatus, which leads to attachment and bone loss and eventually to tooth loss if treatment is not provided. When the periodontitis-r...

Detailed Description

Subject recruitment All patients will be recruited from Periodontal Clinics at the participating centres in United Kingdom (Ravenscourt Dental Practice, 5 Ravenscourt avenue, Germany (University Hospi...

Eligibility Criteria

Inclusion

  • Minimum of 12 teeth present
  • Diagnosis of Severe Periodontitis stage III or IV
  • At least one maxillary/ mandibular molar with: i) degree III horizontal furcation involvement (at least between 2 roots for maxillary molars) , ii) class B vertical furcation involvement (bone loss up to the middle third of root cones), iii) residual probing pocket depths \> 5 mm in furcation area, iv) maximum mobility degree Iand v) not already accessible for self-performed oral hygiene
  • Received a course of non-surgical periodontal therapy within the past six months

Exclusion

  • Patient:
  • Full mouth plaque score \> 30%
  • A course of antibiotics within the past 3 months
  • Pregnant/lactating women
  • Relevant medical history as evaluated by the examining clinician which may have the potential to affect periodontal surgical treatment
  • Individuals on long-standing (2 or above years) supportive periodontal therapy (SPT) management plans
  • Molar affected by FI:
  • Ongoing endodontic pathology affecting the furcation involved molar, as judged by the examining clinician
  • Previous periodontal surgical treatment to the furcation affected molar within the previous 5 years
  • Endodontically treated molar tooth without a full coverage restoration
  • 'Unrestorable' molar tooth (lacking adequate tooth structure to provide a restoration) as deemed by the examining clinician.
  • Molar tooth acting as a bridge abutment
  • The presence of occlusal dysfunction as assessed by the examining clinician

Key Trial Info

Start Date :

April 21 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2029

Estimated Enrollment :

59 Patients enrolled

Trial Details

Trial ID

NCT05237401

Start Date

April 21 2022

End Date

January 1 2029

Last Update

September 30 2025

Active Locations (1)

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1

King's College London

London, United Kingdom