Status:
RECRUITING
Prehabilitation for Patients Awaiting Liver Transplantation
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborating Sponsors:
Canadian Donation and Transplantation Research Program
Canadian Association for the Study of the Liver
Conditions:
Cirrhosis, Liver
Liver Transplantation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study will assess the feasibility, safety and effectiveness of a structured prehabilitation program combining exercise training, nutritional optimization and psychological support for patients wi...
Detailed Description
Due to their chronic liver disease, patients with cirrhosis awaiting liver transplantation develop low muscle mass, poor nutritional status and decreased reserves putting them at high risk of postoper...
Eligibility Criteria
Inclusion
- Age above 18 years
- Diagnosis of cirrhosis, based on a combination of clinical, laboratory, imaging, or histology
- Active on the liver transplant waiting list of the MUHC
Exclusion
- Biological Model for End Stage Liver Disease \>20
- Hepatic decompensation within the last month
- High risk varices not on primary or secondary prevention
- Recurrent large volume paracentesis
- Persistent hepatic encephalopathy
- Platelets \<20,000/µL, or hemoglobin \<80g/L
- Altered hemodynamics
- Significant heart disease
- Awaiting combined organ transplantation
- Awaiting repeat liver transplantation
- Condition limiting mobilization and/or exercise, or recurrent falls
Key Trial Info
Start Date :
February 23 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT05237583
Start Date
February 23 2022
End Date
July 1 2025
Last Update
December 5 2024
Active Locations (1)
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1
McGill University Health Centre
Montreal, Quebec, Canada, H3G1A4