Status:
COMPLETED
Survivorship Post-HCT Optimization Program
Lead Sponsor:
Duke University
Conditions:
Hematologic Malignancy
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this project is to investigate the effects of 12 weeks of high-intensity interval training (HIIT) and resistance training on several domains of health including physical function, cogni...
Eligibility Criteria
Inclusion
- Patient
- ≥18 years old
- English speaking
- Within 90 ± 30 days post allogenic HCT
- Caregiver
- ≥18 years old
- English speaking
- Providing post-discharge care for the patient who has undergone HCT
- Patient and Caregiver
Exclusion
- Have an absolute contraindication to exercise including a recent acute cardiac event (\<6 months), unstable angina, uncontrolled dysthymias causing symptoms or hemodynamic compromise, symptomatic aortic stenosis, uncontrolled symptomatic heart failure, acute pulmonary embolus, acute myocarditis or pericarditis, suspects or known dissecting aneurism, or coronary artery disease.
- In addition to these absolute contraindications, the patient and caregiver will complete cardiopulmonary exercise testing (CPET) where the heart rate and heart rhythm will be monitored via a 12-lead ECG before, during, and after the test. The results from the CPET will be reviewed by a physician before the subject is cleared to participate in the HIIT and resistance training program. If the participant is not cleared by the physician following the CPET, then the patient and his or her caregiver will not be eligible to participate in the study.
Key Trial Info
Start Date :
December 2 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 23 2025
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05238376
Start Date
December 2 2022
End Date
March 23 2025
Last Update
September 26 2025
Active Locations (1)
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1
Duke Adult Blood and Marrow Transplant Clinic
Durham, North Carolina, United States, 27705