Status:

COMPLETED

A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease

Lead Sponsor:

Aramis Biosciences, Inc.

Conditions:

Dry Eye Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The objectives of this trial are to assess the safety, tolerability and efficacy of A197 ophthalmic solution in comparison to a vehicle control in the treatment of subjects with Dry Eye Disease.

Eligibility Criteria

Inclusion

  • Written informed consent must be obtained prior to any study-related assessments
  • Have a history of Dry Eye Disease in both eyes for at least 12 months prior to Visit 1
  • Willing and able to follow instructions and can be present for required study visits

Exclusion

  • Women who are pregnant or breastfeeding
  • Use of topical ophthalmic medications, artificial tears, eye drops and gels in either eye
  • Use of contact lenses within 90 days prior to Visit 1 and throughout the study
  • Have had an ocular infection in either eye within 90 days prior to Visit 1

Key Trial Info

Start Date :

January 25 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 24 2023

Estimated Enrollment :

207 Patients enrolled

Trial Details

Trial ID

NCT05238597

Start Date

January 25 2022

End Date

January 24 2023

Last Update

May 16 2023

Active Locations (24)

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Page 1 of 6 (24 locations)

1

Aramis Site 113

Birmingham, Alabama, United States, 35233

2

Aramis Site 121

Garden Grove, California, United States, 92843

3

Aramis Site 120

Glendale, California, United States, 95817

4

Aramis Site 106

Long Beach, California, United States, 90805