Status:
UNKNOWN
Safety and Tolerability of Nitro for Radial Artery Dilation
Lead Sponsor:
Thomas Jefferson University
Conditions:
Artery; Dilatation
Eligibility:
All Genders
18+ years
Phase:
EARLY_PHASE1
Brief Summary
Phase 1, single-center, open-label clinical study to assess the safety and efficacy of topical nitroglycerin on dilation of the radial artery. Subjects will receive nitroglycerin ointment prior to sch...
Detailed Description
This is a phase I study evaluating the safety, tolerability, and efficacy of topical nitroglycerin prior to percutaneous coronary intervention (PCI). Although the ultimate plan is to evaluate this int...
Eligibility Criteria
Inclusion
- Scheduled to undergo PCI using TRA in the cardiac catheterization laboratory
Exclusion
- Known nitrate allergy
- Baseline hypotension with systolic blood pressure \<90mmHg
- Absence of radial artery blood flow in one or both arms
- Presence or history of liver, rheumatologic, or chronic kidney disease
- Current treatment with any vasodilator therapy (eg. Sildenafil)
- Radial artery catheterization \<30 days prior to enrollment
- Active site infection
- AV-fistula or prior radial artery harvest for bypass surgery
- Abnormal Barbeau test
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT05239013
Start Date
May 1 2022
End Date
March 1 2023
Last Update
April 6 2022
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.