Status:
UNKNOWN
Individual Dosing of Levothyroxine After Thyroidectomy
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Thyroid Neoplasms
Hypothyroidism
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Recently, Zaborek et al. raised a Poisson regression model for levothyroxine(LT4) dosing scheme to predict individual dose of LT4 after thyroidectomy: daily LT4 dose=e\[2.02+0.01(W)-0.0037(A )-0.098(F...
Detailed Description
Patients who underwent total/near-total thyroidectomy or completion thyroidectomy and require levothyroxine replacement therapy will be enrolled in this study. They will be randomized distributed into...
Eligibility Criteria
Inclusion
- patients underwent total/near-total thyroidectomy or completion thyroidectomy; patients with benign disease, or low-risk differentiated thyroid cancer, or medullary thyroid cancer who don't need TSH suppressive therapy;
Exclusion
- patients with heart disease or severe liver/kidney insufficiency; patients taking liothyronine in addition to levothyroxine;
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 10 2023
Estimated Enrollment :
202 Patients enrolled
Trial Details
Trial ID
NCT05240911
Start Date
June 1 2022
End Date
June 10 2023
Last Update
May 10 2022
Active Locations (1)
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1
Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310009