Status:
RECRUITING
ERP to Improve Functioning in Veterans With OCD
Lead Sponsor:
VA Office of Research and Development
Conditions:
Obsessive Compulsive Disorder (OCD)
Comorbid Post-Traumatic Stress Disorder and OCD
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherap...
Detailed Description
The proposed 4-year multisite RCT will compare outcomes of VTH-delivered ERP to those of a stress management training control condition among 160 Veterans with OCD. Half of the sample with have comorb...
Eligibility Criteria
Inclusion
- Veterans having a primary diagnosis of Obsessive Compulsive Disorder (OCD)(50% of sample) and comorbid OCD and Post-traumatic stress disorder (PTSD) (50% of sample) who are receiving care from the Michael E. DeBakey VA Medical Center (MEDVAMC) in Houston, TX; the Ralph H. Johnson VA Medical Center in Charleston, SC; the VISN 20 Clinical Resource Hub which provides telehealth services to Washington, Oregon, and Alaska: the VISN 2 Clinical Resource Hub which provides telehealth services to New Jersey, New York, and northern Pennsylvania, and the VISN 6 Clinical Resource Hub which provides telehealth services to North Carolina and Virginia.
- Willingness to participate in Exposure and Response Prevention(ERP)
Exclusion
- Significant cognitive impairment or conditions that threaten safety (current psychosis, mania, imminent suicidality including plan or intent, and treatment-interfering moderate to severe substance use).
- Potential participants taking psychotropic medications must be on a stable dose of these medications for at least 6 weeks prior to study enrollment.
Key Trial Info
Start Date :
October 3 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2026
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT05240924
Start Date
October 3 2022
End Date
May 31 2026
Last Update
November 13 2025
Active Locations (18)
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1
East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ
East Orange, New Jersey, United States, 07018
2
VA Western New York Healthcare System, Buffalo, NY
Buffalo, New York, United States, 14215-1129
3
VA NY Harbor Healthcare System, New York, NY
New York, New York, United States, 10010-5011
4
Northport VA Medical Center, Northport, NY
Northport, New York, United States, 11768-2200