Status:

UNKNOWN

Effects of Nitrate-rich Beetroot Juice in Pregnant Women With High Blood Pressure

Lead Sponsor:

Karolinska Institutet

Collaborating Sponsors:

The Swedish Research Council

Swedish Heart Lung Foundation

Conditions:

Preeclampsia

Hypertension

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

BACKGROUND: Preeclampsia (PE) is a serious syndrome that affects 3-7% of all pregnant women. PE is characterized by hypertension and kidney problems after the 20th week of pregnancy and is associated ...

Detailed Description

OVERALL PURPOSE: 1\. Study the underlying disease mechanisms in preeclampsia Investigate the physiological effects of dietary nitrate in preeclampsia, in order to increase the production of nitric ox...

Eligibility Criteria

Inclusion

  • Adult and decision-making patient who:
  • is pregnant from week 20
  • has normal blood pressure (controls) or high blood pressure during the current pregnancy (either chronic hypertension, gestational hypertension or preeclampsia)
  • are cared for at Danderyd Hospital (Women's Clinic; Obstetrics and Gynecology)

Exclusion

  • Type 1 diabetes
  • Vegetarians and vegans
  • Regular use/need for proton pump inhibitors (PPi)
  • Smoker

Key Trial Info

Start Date :

January 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 30 2023

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05241327

Start Date

January 1 2022

End Date

May 30 2023

Last Update

February 15 2022

Active Locations (1)

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Danderyd Hospital

Stockholm, Sweden, SE-18257