Status:
COMPLETED
Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis
Lead Sponsor:
Souzy Kamal
Conditions:
Periodontitis Chronic Generalized Moderate
Eligibility:
All Genders
25-45 years
Phase:
PHASE4
Brief Summary
Background: Phytotherapeutics is widely used nowadays as an adjunct to scaling and root planing (SRP) to modulate inflammatory host response and eradicate microbes. Matrix metalloproteinase-8 (MMP-8) ...
Eligibility Criteria
Inclusion
- systemically healthy individuals of both sexes having moderate periodontitis (stage II), CAL 3-4mm, with an age ranging from 25 to 45 years old.
- patients with no history of previous periodontal therapy or taken any antibiotic therapy for the past six months
Exclusion
- history of smoking, previous adverse reaction to the products (or similar products) used in this study, grade C category that has rapid rate of progression, and pregnant or lactating women
Key Trial Info
Start Date :
July 6 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 4 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05241509
Start Date
July 6 2019
End Date
December 4 2021
Last Update
February 15 2022
Active Locations (1)
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1
department of periodontology. Faculty of dentistry. Alexandria University
Alexandria, Egypt, 21521