Status:

COMPLETED

Effect of EMST Systemic Inflammation and Oxidative Stress in Patients With Moderate OSAS

Lead Sponsor:

Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital

Conditions:

Obstructive Sleep Apnea

Oxidative Stress

Eligibility:

MALE

19-60 years

Phase:

NA

Brief Summary

It was aimed to investigate the effect of expiratory muscle strength training (EMST) applied at different intensities on systemic inflammation and oxidative stress in patients with moderate obstructiv...

Detailed Description

Primary outcome measures are; disease severity, oxidative stress index and systemic inflammation. Secondary outcome measurements are; disease-related symptoms, exercise capacity, respiratory muscle s...

Eligibility Criteria

Inclusion

  • Male patients diagnosed with moderate OSAS by polysomnography in the Sleep Center of Ahi Evren Thoracic and Cardiovascular Surgery Training and Research Hospital,
  • Those who are between 19-60 years old,
  • Stable general health status,
  • Volunteer to participate in the research,
  • Not using NIMV device,
  • 5\) Patients who do not have a mental problem that will prevent cooperation will be included.

Exclusion

  • Female gender,
  • Having a previous stroke,
  • Having an overlap syndrome,
  • Having any neurological, psychological or cardiac disease,
  • Uncontrolled hypertension and high blood glucose levels,
  • Severe obstructive nasal disease,
  • History of previous oropharyngeal surgery
  • Having a body mass index of 40 kg/m2 or more,
  • Using drugs, alcohol, sedative and hypnotic drugs,
  • Having a cognitive problem

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2023

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT05242406

Start Date

June 1 2022

End Date

April 1 2023

Last Update

August 14 2023

Active Locations (1)

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Trabzon Ahi Evren Thoracic and Cardiovascular Surgery Training and Research Hospital

Ortahi̇sar, Trabzon, Turkey (Türkiye), 61100