Status:
COMPLETED
Targeting Aging and Promoting Longevity with Exogenous Nucleotides (TALENTs)
Lead Sponsor:
Peking University
Conditions:
Aging
Eligibility:
All Genders
60-70 years
Phase:
NA
Brief Summary
To investigate the effects of dietary nucleotides (NTs) as an anti-aging supplement, a clinical trial is carried as a randomized, double-blind, parallel design, placebo-controlled. A total of 120 subj...
Detailed Description
To explore the anti-aging effects of NTs and the regulation of aging-related diseases, this study plans to recruit 120 people as subjects and conduct randomized controlled trials with NTs as an interv...
Eligibility Criteria
Inclusion
- Male/females of 60 to 70 years of age
- No serious physical or mental illness
- Able to provide written Informed Consent
- Able to follow verbal and written study directions
- Must not be taking or be willing to take any supplements containing any form of nucleotides for one year prior to baseline and for the duration of the study.
- Able to maintain consistent diet and lifestyle habits throughout the study
- Willing to consume assigned supplement (NTs or placebo) for 4 months
Exclusion
- Participants on the current use of prescription or over-the-counter nucleotides
- Having abnormal screening laboratory test values or other lab test result(s) that would preclude study participation in the judgment of the investigator
- Documented presence of atherosclerotic disease and/or cardiopulmonary disease
- History of drug or alcohol abuse
- History of unstable depression or mental illness within the last 6 months for which the investigator believes could impact the participant's ability to comply with study requirements
- Other diseases or medications, according to the investigator, that would interfere directly in the results of the study or jeopardize the health of the participant.
- Currently, or within the past 30 days, enrolled in a different clinical investigation
- Inability to provide a venous blood sample
- Unable or unwilling to provide written informed consent for participation in the study
Key Trial Info
Start Date :
August 23 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 29 2023
Estimated Enrollment :
122 Patients enrolled
Trial Details
Trial ID
NCT05243108
Start Date
August 23 2022
End Date
March 29 2023
Last Update
January 29 2025
Active Locations (1)
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1
Talents project team
Chengdu, Sichuan, China, 610095