Status:

RECRUITING

Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer

Lead Sponsor:

Shanghai 10th People's Hospital

Conditions:

Rectum Cancer

Stoma Colostomy

Eligibility:

All Genders

18+ years

Brief Summary

RATIONALE: Colorectal cancer is one of the most common cancers. However, approaches to minimize surgical trauma, preserve anal function, avoid abdominal stoma, and improve quality of life for patients...

Eligibility Criteria

Inclusion

  • Histological proof of newly diagnosed primary adenocarcinoma of the rectum
  • The lower edge of tumor \< 3 cm from the dentate line
  • Clinical T stage ≤ T3

Exclusion

  • The lower edge of tumor \< 1 cm from the dentate line
  • Locally advanced stage of tumor
  • Presence of metastatic disease or recurrent rectal tumor
  • Concomitant malignancies
  • Concurrent uncontrolled medical conditions
  • Impaired anal function before surgery
  • Presence of acute bowel obstruction or bowel perforation caused by cancer
  • Pregnancy or breast feeding

Key Trial Info

Start Date :

May 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2026

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT05245565

Start Date

May 1 2021

End Date

May 1 2026

Last Update

April 13 2023

Active Locations (1)

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Shanghai Tenth People's Hospital

Shanghai, Shanghai Municipality, China, 200072