Status:

UNKNOWN

Ergospirometry in Paroxysmal Atrial Fibrillation Prognosis

Lead Sponsor:

Aristotle University Of Thessaloniki

Collaborating Sponsors:

General Hospital Of Thessaloniki Ippokratio

Conditions:

Atrial Fibrillation

Atrial Arrhythmia

Eligibility:

All Genders

18+ years

Brief Summary

An observational, prospective, cohort study aiming to assess the potential predictive role of cardiopulmonary exercise testing in the prognosis of paroxysmal atrial fibrillation, in combination with e...

Detailed Description

The "ParoxysmaL Atrial fibrillation prognosis based on Cardiopulmonary Exercise test data and novel echocardiographic and plasma BiOchemical indices" (PLACEBO) trial comprises an observational, prospe...

Eligibility Criteria

Inclusion

  • Patients with paroxysmal atrial fibrillation (in sinus rhythm during baseline evaluation)
  • Age \> 18 years
  • Capability of providing written consent
  • Patients able to undergo cardiopulmonary exercise testing
  • Patients able to comply with the follow-up schedule of the study

Exclusion

  • Patients with structural cardiomyopathy
  • Patients with congenital heart disease
  • Patients with permanent atrial fibrillation
  • Patients who have undergone atrial fibrillation ablation
  • Patients with implanted cardiac devices for primary or secondary prevention
  • Patients with recent (within the last month) acute coronary syndrome
  • Patients with heart failure with reduced ejection fraction (HFrEF) or end-stage renal disease
  • Patients with autoimmune diseases or active malignancies
  • Patients with uncontrolled thyroid disease
  • Patients unable to undergo cardiopulmonary exercise testing due to disability or motility issues
  • Patients who present with contraindications for cardiopulmonary exercise testing
  • Patients unable to provide written consent
  • Patients with poor echocardiographic images
  • Patients unable to undergo spirometry
  • Patients unable to comply with the follow-up schedule of the study
  • Patients with uncontrolled hypertension
  • Patients who have undergone recent (within the last 2 months) surgery
  • Pregnancy

Key Trial Info

Start Date :

December 10 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 10 2024

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05246423

Start Date

December 10 2020

End Date

December 10 2024

Last Update

February 18 2022

Active Locations (1)

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Ippokratio General Hospital

Thessaloniki, Thessaloniki, Greece, 54642