Status:
COMPLETED
Assessment of Fluctuating Parkinson's Disease With Sensor-based Home Monitoring
Lead Sponsor:
Sheba Medical Center
Collaborating Sponsors:
AbbVie
Intel Electronics Ltd.
Conditions:
Parkinson Disease
Eligibility:
All Genders
30+ years
Brief Summary
The aim of this study is to implement home-based monitoring (HBM) using remote-capture wearable devices and patient reported outcomes (PROs) in a rather homogeneous subgroup of advanced Parkinson's Di...
Detailed Description
Parkinson's Disease (PD) is a neuro-degenerative disorder affecting millions of people worldwide. PD is associated with both motor and non-motor symptoms that affect patients' functioning and Quality ...
Eligibility Criteria
Inclusion
- Diagnosis of idiopathic Parkinson's disease for at least 5 years
- Males or females over the age of 30
- Patients treated with oral levodopa (3 daily doses or more), reporting motor fluctuations and (preferably) with l-dopa-induced dyskinesia
- UPDRS-MDS 4.4 functional impact of fluctuations (mild + severe, 2-4)
- Hoehn \&Yahr stage 1-3 while ON
- Ability to operate smartphone technology in the household
- Mini-Mental State Examination score \>20
Exclusion
- Cognitive or psychiatric impairment that would preclude study participation as determined by the principal investigator
- Additional major comorbidities
- Levodopa-resistant tremor (tremor during ON)
- Levodopa-resistant freezing (freezing during ON)
- Previous surgical treatment for PD
Key Trial Info
Start Date :
November 3 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 24 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT05247294
Start Date
November 3 2019
End Date
February 24 2021
Last Update
February 18 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Movement Disorders Institution, Sheba Medical Center
Ramat Gan, Israel