Status:
COMPLETED
Platelet Aggregation and Adenosine Levels Among Patients Taking Ticagrelor or Prasugrel
Lead Sponsor:
University of Sao Paulo
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
Prospective, single-center, double blind, double dummy, randomized trial. Platelet function tests and adenosine levels were assessed at baseline and 15 days after taking Ticagrelor with Prasugrel plac...
Detailed Description
This was a prospective, double blinded, randomized trial that compared platelet inhibition and adenosine levels with ticagrelor (180mg loading dose, followed by 90 mg BID) versus prasugrel (60mg loadi...
Eligibility Criteria
Inclusion
- between 18 and 75 years old
- were on aspirin
- without P2Y12 inhibitor at baseline
- \> 1 year after documented acute coronary syndrome
Exclusion
- use of oral anticoagulation or P2Y12 at baseline
- Weight \< 60kg
- History of tia or stroke
- Any coagulation disorders
- Refuse to sign the written consent
Key Trial Info
Start Date :
March 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 20 2021
Estimated Enrollment :
87 Patients enrolled
Trial Details
Trial ID
NCT05247385
Start Date
March 20 2017
End Date
December 20 2021
Last Update
February 18 2022
Active Locations (1)
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1
Heart Institute (InCor) / University of São Paulo
São Paulo, São Paulo, Brazil, 05403-000