Status:

UNKNOWN

"Efficacy of Once Weekly GLP 1 Analogue: Semaglutide. A Multicenter Experience From Pakistan."

Lead Sponsor:

Aga Khan University

Collaborating Sponsors:

Rehman Medical Institute - RMI

Conditions:

Diabetes Mellitus, Type 2

Weight Change, Body

Eligibility:

All Genders

18+ years

Phase:

EARLY_PHASE1

Brief Summary

A prospective interventional trial for 9 months will be carried out on 300 type-2 diabetes mellitus volunteer patients who are above 18-year-old and participants will be selected through consecutive s...

Detailed Description

Patients will be recruited from all the 12 centers included in the trial across Pakistan and data will be electronically transferred to the main center. All GLP-1 naive patients fulfilling the inclusi...

Eligibility Criteria

Inclusion

  • Both male and female Type 2 Diabetic patients with age ≥18 years.
  • Patients with HbA1c ≥ 7.5 % - ≤ 10.0%
  • Patients with BMI ≥ 30

Exclusion

  • Patients with Type 1 Diabetes Mellitus
  • Patients with Gestational Diabetes Mellitus.
  • Patients with Chronic Renal Failure with eGFR of ≤ 30ml/min
  • Patient already on another GLP 1 analogue
  • The patient stopped any GLP1 analogue treatment less than 3 months back.
  • Patients with history of chronic pancreatitis or pancreatic cancer.

Key Trial Info

Start Date :

March 10 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT05249881

Start Date

March 10 2022

End Date

December 1 2022

Last Update

August 5 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Rehman Medical Institute

Peshawar, KPK, Pakistan, 25100

2

Aga Khan University

Karachi, Sindh, Pakistan, 74800