Status:
COMPLETED
Skeletal Muscle Oxygenation in Patients With Chronic Kidney Disease Stage 2, 3 and 4
Lead Sponsor:
Aristotle University Of Thessaloniki
Conditions:
Chronic Kidney Diseases
Eligibility:
All Genders
18+ years
Brief Summary
Endothelial dysfunction occurs early in chronic kidney disease (CKD) and is associated with target organ damage, progression of renal injury, cardiovascular events, and mortality. Near-infrared spectr...
Detailed Description
This is a cross-sectional study performed in the Department of Nephrology, Hippokration Hospital, Thessaloniki, Greece. For the purposes of this study, consecutive CKD patients stage 2-4 regularly fol...
Eligibility Criteria
Inclusion
- Age\>18 years
- Patients with CKD stage 2, 3a, 3b, 4 (CKD-EPI eGFR: \<90 and ≥30mL / min / 1.73m2) and controls without CKD
- Provision of informed written signed consent prior to study entry
Exclusion
- Kidney transplant recipients
- Myocardial infarction or unstable angina episode within the past 3 months, or congestive heart failure class III-IV according to New York Heart Association criteria
- Patients with history of stroke, dementia or other severe neurologic disorders (e.g. Parkinson's disease, multiple sclerosis, etc)
- Patients with severe mental disorders
- History of drug or alcohol abuse
- Patients with muscle disorders
- Active malignant disease or other comorbidity with poor prognosis
- Active infection or relevant inter-current illness
- Pregnancy
Key Trial Info
Start Date :
June 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 30 2022
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05250167
Start Date
June 1 2021
End Date
May 30 2022
Last Update
July 21 2022
Active Locations (1)
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1
Department of Nephrology, Hippokration Hospital
Thessaloniki, Greece, 54642