Status:

COMPLETED

Tolterodine Relieves Overactive Bladder Symptoms in Women With Moderate-to-severe Obstructive Sleep Apnea Syndrome

Lead Sponsor:

Yuzuncu Yil University

Conditions:

Overactive Bladder

Obstructive Sleep Apnea

Eligibility:

FEMALE

18-60 years

Phase:

PHASE4

Brief Summary

In this study, we aim to determine whether combined tolterodine and CPAP therapy is a more effective treatment for patients with OSAS than CPAP treatment only.

Eligibility Criteria

Inclusion

  • Women older than 18 who underwent polysomnography test with suspicion of OSAS between 01.06.2020-01.01.2022 were enrolled in the study
  • Patients with AHI ≥15 (moderate or severe) and OAB-V8≥8 were considered eligible for the study and randomized in two groups to receive either CPAP treatment only or CPAP treatment with tolterodine tartrate

Exclusion

  • Patients diagnosed with neurological diseases, diabetes mellitus, congestive heart failure, infection, hematuria, urolithiasis, urinary tumors, and urinary retention were excluded from the study. Also, a history of lower urinary tract surgery and medication due to lower urinary tract symptoms were the exclusion criteria.

Key Trial Info

Start Date :

June 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05250245

Start Date

June 1 2020

End Date

January 1 2022

Last Update

February 22 2022

Active Locations (1)

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Yuzuncu Yıl University

Van, Turkey (Türkiye)