Status:

COMPLETED

Thyroid Function in Liver Cirrhosis: Is it Affected?

Lead Sponsor:

Mansoura University

Conditions:

Liver Cirrhosis

Eligibility:

All Genders

18-80 years

Brief Summary

In patient with liver cirrhosis ,thyroid functions are largely affected in our study we studied the changes in thyroid functions in patients with liver cirrhosis

Detailed Description

In clinical terms, cirrhosis is described as are either "compensated" or "decompensated." Decompensation means cirrhosis complicated by one or more of the following features: jaundice, ascites, hepati...

Eligibility Criteria

Inclusion

  • Sex: both
  • Age:18-80 years.
  • Known and established cases of cirrhosis liver by clinical, radiological (ultrasound abdomen), and biochemical study.
  • Patients who were willing to part of study after consent.
  • Control - Apparently healthy age- and sex-matched individuals between 18 and 80 years.

Exclusion

  • Age: below 18 or above 80 years old.
  • Known cases of thyroid disorder without liver cirrhosis.
  • Patient with history of organ failure, cancer, radio or chemotherapy and individual with active infection such as bone and muscle disease, cardiac, pancreatic (diabetes), chronic kidney disease, nephrotic syndrome.
  • Patient using drugs that interfere with thyroid metabolism such as levothyroxine, propylthiouracil, carbimazole, iodine, amiodarone, and beta-blockers.

Key Trial Info

Start Date :

May 18 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 18 2022

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT05250401

Start Date

May 18 2021

End Date

January 18 2022

Last Update

February 22 2022

Active Locations (1)

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MansouraU

Al Mansurah, Egypt