Status:

COMPLETED

Comparative Quantification of MTX and Its Metabolites Post Glucarpidase

Lead Sponsor:

Charite University, Berlin, Germany

Conditions:

Lymphoma

Acute Lymphatic Leukemia

Eligibility:

All Genders

Brief Summary

Acidification (i.e., addition of hydrochloric acid) of plasma samples from patients who have received Glucarpidase post high-dose MTX treatment is regarded as a necessary preanalytic step to avoid fur...

Detailed Description

Stored plasma samples (paired - acidified and non-acidified) from the specimens collection ('Tumorbiobank') of the Charité Comprehensive Cancer Center will be analysed by HPLC/MS. A total of 136 samp...

Eligibility Criteria

Inclusion

  • Treatment with Glucarpidase

Exclusion

  • Lacking patient consent

Key Trial Info

Start Date :

July 6 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT05250869

Start Date

July 6 2022

End Date

December 31 2022

Last Update

July 22 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Charité - Universitätsmedizin Berlin

Berlin, Germany, 12200